nipt test inconclusive twicenipt test inconclusive twice

Friend opening my baby items for their own baby. Would I consider diagnostic tests like amniocentesis or CVS? I didn't do a NIPT (just the NT scan) so no personal experience! Find advice, support and good company (and some stuff just for fun). The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. Has anyone had this? Australian post natal pack provided to all new parents. Are there other tests I can take to find out my risks? Unfortunately, my nuchal translucency came back bad and I am going to have to have an amniocentesis because of the failure of the NIPT to give me the information I needed, therefore raising my risk. I am 36 and unfortunately very much plus size. It's not like my weight was a surprise to them. I've had he NIPT test twice now and had it come back for low fetal DNA. 1997-2023 BabyCenter, LLC, a Ziff Davis company. NIPT cant screen for all chromosomal or genetic conditions. I just did a retest last week because mine came back inconclusive!! When I went back for a second blood draw, they took two tubes of blood. There is a 0% chance of survival with this condition so we are looking into terminating in the next few days not my rainbow baby after all.. NIPT stands for noninvasive prenatal testing. So I'm not sure how it was for you. I was 164 pre pregnancy and 184 now. Group Black's collective includes Essence, The Shade Room and Naturally Curly. My anatomy ultrasound is on Friday. Both said due to low fetal DNA at 2.6% and 2.7% respectively. Lab is saying I could try a third time but no guarantees it will work. The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. This is called the fetal fraction. I found out we are having a little girl! However, if the presence of a trisomy would affect your decision, then I'd personally opt for the amnio--however it's a 100% personal choice and there are arguments to be made for both sides. Were my expectations of postpartum help from my mom Press J to jump to the feed. Guess how I found that out? She didnt suggest further testing. We strive to provide you with a high quality community experience. Your healthcare provider will discuss all your prenatal screening options, including NIPT. I didn't even want them to do that. Thank you! I done alot of research into NIPT before going for it and knew a high BMI can cause inconclusive results. Dont be afraid to ask questions. Your post will be hidden and deleted by moderators. Another inconclusive result. Its important to talk to your healthcare provider about what your NIPT is screening for. Overwhelmed and frustrated by weight gain. Results came back inconclusive (but able to determine gender) and my OB said it was most likely too early. Same thing happened to me. Group Black's collective includes Essence, The Shade Room and Naturally Curly. 15/01/2022 20:53. Same situation here! Your healthcare provider can answer any questions you have, but ultimately you have to decide how a genetic or chromosomal disorder affects you and your family based on your situation. But that's my personal non-expert opinion. Just want to complain somewhere. Hi friend. The #1 app for tracking pregnancy and baby growth. NIPT tests dont diagnose conditions. Use of this site is subject to our terms of use and privacy policy. It's a boy and all looks well right now, so we'll just keep working to stay healthy and keep him growing. Based on the results of the NIPT test, your obstetrician may recommend diagnostic tests. Are you doing the NT scan & bloods as well? you can always do amnio if you need results. it seems to be more common than we think. I was 11 weeks and 12.5 weeks for mine. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Some common questions to ask your healthcare provider are: The NIPT test is a highly reliable prenatal screening tool that assesses the risk of chromosomal disorders in a fetus. endstream endobj 70 0 obj <>/Metadata 17 0 R/PageLayout/OneColumn/Pages 67 0 R/StructTreeRoot 23 0 R/Type/Catalog/ViewerPreferences<>>> endobj 71 0 obj <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageC]/XObject<>>>/Rotate 0/StructParents 0/Tabs/S/Type/Page>> endobj 72 0 obj <>stream I done alot of research into NIPT before going for it and knew a high BMI can cause inconclusive results. I have read this is an issue for plus size women and . We strive to provide you with a high quality community experience. Please specify a reason for deleting this reply from the community. Originally my doctor said we would take another blood sample once I was further along around 16 weeks and try again if it didn't work initially. Same thing happened to me. The test can also determine the sex of the fetus. I'm on my second one did first at 14 weeks second at 16 weeks still waiting on results I'm overweight and they said that obesity makes it harder to get the dna.ive had several scans and no soft markers found. A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. . Diagnostic tests give a definitive answer about whether the fetus has a specific condition. The result will show if theres an increased or decreased risk for a fetus to have the condition being screened. :). Any of you ladies have an update? X. I am overweight. Just got my results back yesterday with a BMI of 47. He sent me to do echocardiography which also was good and show no signs for pathologies. Many factors may go into your decision to have NIPT and prenatal genetic testing in general. E@Gpc 8Op!ISHiT7{;-N/OM7Mq+YV1d)|\i-V;`]tyTAHqAFWR This just happened to me today, I didn't really want the DNA test but my husband wanted peace of mind. H Hawaiimomma22 Nov 30, 2017 at 12:44 AM @veneziana, What was the outcome? As far as 16 weeks ultrasound, sex was pretty obvious on mine . Group Black's collective includes Essence, The Shade Room and Naturally Curly. I have read this is an issue for plus size women and the other factor is age. Myriad is able to magnify the fetal fraction found in your blood.. They tell your provider how likely it is that a condition exists. Check with your insurance provider before testing to be sure. Please specify a reason for deleting this reply from the community. Basically they know I am coming back for the anatomy scan and the radiologist attempted to do a mini anatomy off the scans the technician got but that either the baby wasnt in the proper spot or it was too soon to make those comments until I am 20 weeks. My doc told me 2 inconclusive tests raises the risk level significantly in my age. Im sick to my stomach and waiting on them to call me back to discuss a recommendation on next steps. Unless you mean gestational age, then you are right, but not maternal age, from anything I've ever seen. Its nerve racking, but I'm hoping to hear some good news soon. Getting a noninvasive pregnancy screening or other prenatal genetic test is up to you. If your baby still has a heartbeat now, maybe that means that the baby doesnt have that. (https://pubmed.ncbi.nlm.nih.gov/26781507/), Visitation, mask requirements and COVID-19 information. Create an account or log in to participate. I had to wait about 10 days for bouth times I did NIPT, only to get inconclusive results. So odd! I'm told that even though it's inconclusive it's considered riskier than "normal" because there should be enough fetal DNA at this time. yes, I have the 12 week scan scheduled for tomorrow evening + bloods then - maybe it will be a different lab this time and it will work. think twice before sharing personal details, foster a friendly and supportive environment, remove fake accounts, spam and misinformation, delete posts that violate our community guidelines, reviewed by our medical review board and team of experts. My BMI is a bit high and I've read that can be a reason. You definitely are not obese! It set my expectations unreasonably high. Maybe that is the the reason. Hope you are getting all the support you need and sending good healthy babe energy your way! Learn more about our guidelines Ive done nipt through generations and Harmony both reputable brands and they would never give results with that low of a fraction, as it could come from contamination from say, the person drawing the bloods or the one analysing touching the tube to read results. I hate the thought of ending your babys life especially if the doctors have it wrong. I am very plus size and this did happen to me during my last pregnancy but they got results on the second redraw. I'm now worried something could be wrong with my baby. , I agree with PP. Had my redraw at 13+2, and results have come back the same, inconclusive due to low fetal fraction. *_xCeEm Di?z&>#m`X_ )= Disneybaby12345 01/01/21 Hello all, I am a second time mum with a long and complex pregnancy and birth history. How far along were you when you took each one? However my 12 weeks NT scan and EFTS blood test both came back normal/ low . I would be very frustrated. I dont think Im obese but definitely cons. Had to redraw today and start the waiting process all over. I have never heard of two inconclusive results! All rights reserved. The first test they ran apparently i did not have enough fetal DNA i took another one and the same results, should I be concerned? I fully understand your need for answers - I felt exactly the same way and its much better to have a yes/no answer through CVS/amniocentesis than keep guessing etc. I agree with PP. Thats why the screening isnt performed until 10 weeks into the pregnancy. Noninvasive pregnancy screening tests are a personal choice. I'm panicking now because I'm so worried. A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. hYmo6+bDR$EE iZcKZ2,5V~b)%7QGx{8qfs&,9K dbyb:,Xg1cekX3)-l`Gj%SV0H@1#43*a?+V1bM4^%}*&29Li1I=&~~K&a/e2,VaLFEZE]&7_4NO\Vq9z2.U\b1)0[$@'NmY=B(db~O^6jRJfbZ&\fMeY?RPu A]LaR2rt$\.E=_&ShK+05}rYo"&7xJ|10&,*NOop;~\@`zPd40`Qq[BlJMOnsgU*|]yepYE.+yf We are going to do the quad screen and a detailed ultrasound next week. NIPT test done twice.with inconclusive results twice. Talk to your healthcare provider or a genetic counselor about your concerns. This testing analyzes small fragments of DNA that are circulating in a pregnant woman's blood. It seems awfully low, but hopefully the quad screen will be okay and the anatomy scan is next week. Well, my redraw came back inconclusive, but the NT ultrasounds were reassuring (I am carrying twins). Inconclusive NIPT results twice : hello, just wondering if this has happened to anyone? Your healthcare provider will receive your test results first, then share the results with you. Amnio specialist also told me that low fetal fraction can be because of placenta. The NIPT measures the fetal cfDNA in the mother's bloodstream, which comes from the placenta. NIPT is a screening test and, therefore, isnt perfect. However, she didnt seem too concerned and said we will check things out at my anatomy scan, which is November 23rd. It has to be at least above 4 percent to give a conclusive result. When I called for test results over a week later, they said they had needed to test the second tube as the first had failed. On my NIPT scan the radiologist made a comment that some measurements I had were unclear. Create an account or log in to participate. You apparently have too much blood for an accurate reading. Has this happened to anyone else? Hi all, just an update. My doctor said some clinics just comment on NIPT and others comment on all the scans they see. In Latvia we have to do first trimester screening where they mesure NT and check Papp-a & HCgb levels. Note that once you confirm, this action cannot be undone. I called the doctors office today to check on my second Panorama test and they informed the test came back again inconclusive due to low fetal fraction. Your test results may sometimes be hard to interpret, so ask your healthcare provider for help if youre unsure. I also did NIPT twice and bouth times it came back inconclusive due to low fetal fraction. Thanks for the advice and suggestions! Ocean/sky themed baby girl nursery - finished at 38+ A hilarious moment that made me excited to have my kid. . I've had he NIPT test twice now and had it come back for low fetal DNA. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. They kinda downplayed it saying it happens a lot, but it still stresses me out a little. A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. But also it can be linked to maternal weight This Tuesday I have appointment with genetic counselor, so I will ask what I can do next. Noninvasive prenatal testing (NIPT), sometimes called noninvasive prenatal screening (NIPS), is a method of determining the risk that the fetus will be born with certain genetic abnormalities. Now doing the waiting game!! I'll be around 18 weeks by then. I dont have any advice. hb``c``Zp7XX8LN`` I'm pretty sure its because I'm overweight lolmanyjow dehydration sounds like a good idea although the first day I went I had puked all morning Anyhow am skipping it now and will just wait till my next appointment which is on the 20th and hopefully we will find out the gender. Hey! We just got our results back and have a perfectly healthy eggo. I'm panicking now because I'm so worried. 20062023 BabyCenter, LLC, a Ziff Davis company. Find advice, support and good company (and some stuff just for fun). (https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3893900/). u 03-(q}|$05`- H320mf`~e0 * They didn't even bother to retest mine when the first try came back inconclusive because they assumed it wouldn't work since I'm obese. Symptmes de grossesse ne jamais ignorer, Moyens naturels pour dclencher l'accouchement. praying for you and your son or daughter to receive good results! NIPT testing doesnt diagnose conditions it only suggests a fetus is more likely to have a particular condition. Press question mark to learn the rest of the keyboard shortcuts, third time mom / due aug 2023 / 30 / she/her. I have also read that certain medications can interfere so that is totally possible that its what happened in your case. Many cover at least a portion. Most labs give separate results for each condition theyre screening for. Inconclusive on gender results? Have had an earlier screening test that suggests a potential problem. This test can be done beginning at 10 weeks of pregnancy. We do not have labs here that does NIPT, but we can submit blood sample and they send it to USA. I have a high risk of 1/175. 4% at least is needed for accuracy. I met with a genetics counselor and decided to do a 3rd round of genetic testing through Myriad! Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. Not all NIPT panels evaluate for the same conditions. Results from first trimester screening came back low for t21, t13, t18 My doctor just did not liked that NT measured 2.6mm and that was the reason she sent me to do NIPT. We do not endorse non-Cleveland Clinic products or services. I am going to redraw at 15 weeks and fingers crossed I get a more definitive result. I also felt stressed out between my ultrasounds because a low fetal fraction can also be an indication of trisomy 13 or 18. We had two failed harmony results, both came back inconclusive because of low dna fraction. I ended up asking for a quad screen (it wasnt covered by my insurance but was like $30) to assess risk for trisomy 21, 18 and spina bifida. It requires drawing blood from the pregnant person only. Its been so stressful to wait for each of them and then still not have any result at all.. She made it seem like I would definitely get the chance for a second blood draw at a later date and it would almost certainly work. Praise post for amazing husbands and good in-laws. Ultimately, we learned we were having a baby girl who did not test positive for trisomy but have still been advised to do an amniocentesis procedure at 16 weeks for ultimate peace of mind. If you dont have insurance or your insurance doesnt cover NIPT tests, you can pay for the test. Has anyone had this happen to them or know someone? endstream endobj 73 0 obj <>stream Theres also the possibility that no test results are given due to insufficient fetal DNA in your blood or difficulty identifying fetal DNA. I am so confused and stressed. Mine came back inconclusive twice. My risk just due age is 1/94 for trisomy 13, 18. Praying for all babies too come back clear and healthy!! Your cells are constantly dividing and creating new cells. Even though my OB told me it likely wasn't the case for me, I was still in panic mode for a while. This happened to me as well. They could have also just waited until 16 weeks for my first blood draw given my weight. hbbd``b` $X-  H *H2M) u$B@> LW@b!3.|` Cleveland Clinics Ob/Gyn & Womens Health Institute is committed to providing world-class care for women of all ages. My doc told me 2 inconclusive tests raises the risk level significantly in my age. rU%`_@j)4KYm9"PR Xb@{i#n->`#4sI2n# ! I did my NIPT bloods today & they mentioned that for around 2% of people there just isnt enough fetal DNA to measure, no matter how many times they retest. NIPT (Harmony test) inconclusive twice. Is this an ivf pregnancy? The first time it came back inconclusive due to low fetal fraction. Use of this site is subject to our terms of use and privacy policy. Disorders affecting sex chromosomes (X and Y). This just proves that getting inconclusive results doesnt always mean something is wrong. If youre having a difficult time or wish to discuss the screenings in more detail, a genetic counselor can help you understand the prenatal testing options and what may be a good fit for you. I think it can be too early when you tested and hopefully that's your case!

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